Damage Control Resuscitation in critical trauma patients

Damage Control Resuscitation (DCR) is a crucial approach in managing critically injured trauma patients, particularly those with severe bleeding and airway management considerations. DCR involves a combination of damage control surgery, permissive hypotension, and hemostatic resuscitation. The primary goal of DCR is to control critical bleeding and trauma-induced coagulopathy, which is essential in preventing further complications and improving patient outcomes (Gando & Hayakawa, 2015; LaGrone, 2023; Wu et al., 2015).

DCR principles have gained widespread acceptance in civilian practice over the past decade due to their effectiveness in preventing and correcting trauma-induced coagulopathy, as well as rapidly controlling hemorrhage. By combining early definitive hemorrhage control, hypotensive resuscitation, and balanced use of blood products, DCR aims to limit blood loss, prevent coagulopathy, and improve patient survival rates (Avery et al., 2020; Jansen et al., 2009).

The use of whole blood (WB) in hemostatic resuscitation has been associated with improved mortality outcomes in major bleeding cases, both in hospital and of significant not, out of hospital by paramedics. Studies support the utilization of WB in trauma patient resuscitation, further emphasizing the importance of appropriate blood product management in DCR (Hazelton et al., 2022).

In both adult and pediatric trauma patients, the principles of DCR remain consistent, focusing on rapid bleeding control, avoidance of hemodilution and related complications, early balanced transfusions with blood products, and the use of hemostatic adjuncts when necessary. These strategies aim to address the "lethal triad" of acute coagulopathy, hypothermia, and acidosis commonly seen in trauma patients (Russell et al., 2023; Kaafarani & Velmahos, 2014).

Overall, DCR plays a vital role in trauma resuscitation, both prehospital and in hospital, by addressing the immediate needs of critically injured patients, such as controlling bleeding, preventing coagulopathy, and maintaining hemostasis. By following DCR principles, healthcare providers can significantly improve patient outcomes and increase the chances of survival in trauma cases (Ramakrishnan & Cattamanchi, 2014; Jacob & Kumar, 2014; Leibner et al., 2020).

References:

  • Avery, P., Morton, S., Tucker, H., Green, L., Weaver, A., & Davenport, R. (2020). Whole blood transfusion versus component therapy in adult trauma patients with acute major haemorrhage. Emergency Medicine Journal, 37(6), 370-378.
    https://doi.org/10.1136/emermed-2019-209040
  • Gando, S. and Hayakawa, M. (2015). Pathophysiology of trauma-induced coagulopathy and management of critical bleeding requiring massive transfusion. Seminars in Thrombosis and Hemostasis, 42(02), 155-165.
    https://doi.org/10.1055/s-0035-1564831
  • Hazelton, J., Oh, J., Ssentongo, P., Seamon, M., Byrne, J., Armen, S., … & Porter, J. (2022). Use of cold-stored whole blood is associated with improved mortality in hemostatic resuscitation of major bleeding. Annals of Surgery Open, 276(4), 579-588.
    https://doi.org/10.1097/sla.0000000000005603
  • Jacob, M. and Kumar, P. (2014). The challenge in management of hemorrhagic shock in trauma. Medical Journal Armed Forces India, 70(2), 163-169.
    https://doi.org/10.1016/j.mjafi.2014.03.001
  • Jansen, J., Thomas, R., Loudon, M., & Brooks, A. (2009). Damage control resuscitation for patients with major trauma. BMJ, 338(jun05 1), b1778-b1778.
    https://doi.org/10.1136/bmj.b1778
  • Kaafarani, H. and Velmahos, G. (2014). Damage control resuscitation in trauma. Scandinavian Journal of Surgery, 103(2), 81-88.
    https://doi.org/10.1177/1457496914524388
  • LaGrone, L. (2023). American association for the surgery of trauma/american college of surgeons committee on trauma: clinical protocol for damage-control resuscitation for the adult trauma patient. Journal of Trauma and Acute Care Surgery, 96(3), 510-520.
    https://doi.org/10.1097/ta.0000000000004088
  • Leibner, E., Andreae, M., Galvagno, S., & Scalea, T. (2020). Damage control resuscitation. Clinical and Experimental Emergency Medicine, 7(1), 5-13.
    https://doi.org/10.15441/ceem.19.089
  • Ramakrishnan, V. and Cattamanchi, S. (2014). Transfusion practices in trauma. Indian Journal of Anaesthesia, 58(5), 609.
    https://doi.org/10.4103/0019-5049.144668
  • Russell, R., Leeper, C., & Spinella, P. (2023). Damage-control resuscitation in pediatric trauma: what you need to know. Journal of Trauma and Acute Care Surgery, 95(4), 472-480.
    https://doi.org/10.1097/ta.0000000000004081
  • Wu, D., Zhou, X., Ye, L., Gan, J., & Zhang, M. (2015). Emergency department crowding and the performance of damage control resuscitation in major trauma patients with hemorrhagic shock. Academic Emergency Medicine, 22(8), 915-921.
    https://doi.org/10.1111/acem.12726


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